Title : Inhibition of the enzymes in the leukotriene and prostaglandin pathways in inflammation by 3-aryl isocoumarins.

Pub. Date : 2016 Nov 29

PMID : 27597418






1 Functional Relationships(s)
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1 The biosynthesis of leukotrienes in one of the arachidonic acid pathways and PGE2 in the other by 5-LOX and mPGES1 respectively, play pivotal roles in augmenting inflammatory responses. Leukotrienes prostaglandin E synthase Mus musculus