Title : Progesterone treatment modulates mRNA OF neurosteroidogenic enzymes in a murine model of multiple sclerosis.

Pub. Date : 2017 Jan

PMID : 27597394






2 Functional Relationships(s)
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1 Using qPCR, we found in steroid-untreated EAE mice decreased mRNAs for the steroidogenic acute regulatory protein (Star), voltage-dependent anion channel (VDAC), P450scc (cholesterol side-chain cleavage), 5alpha-reductase, 3alpha-hydroxysteroid dehydrogenase (3alpha-HSD) and aromatase, whereas levels of 3beta-hydroxysteroid dehydrogenase (3beta-HSD) showed a large intra-group variance. Steroids steroidogenic acute regulatory protein Mus musculus
2 Using qPCR, we found in steroid-untreated EAE mice decreased mRNAs for the steroidogenic acute regulatory protein (Star), voltage-dependent anion channel (VDAC), P450scc (cholesterol side-chain cleavage), 5alpha-reductase, 3alpha-hydroxysteroid dehydrogenase (3alpha-HSD) and aromatase, whereas levels of 3beta-hydroxysteroid dehydrogenase (3beta-HSD) showed a large intra-group variance. Steroids steroidogenic acute regulatory protein Mus musculus