Pub. Date : 2016 Aug 31
PMID : 27577048
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Mutations of isocitrate dehydrogenase 1 (IDH1) and IDH2 in acute myeloid leukemia (AML) cells produce the oncometabolite R-2-hydroxyglutarate (R-2HG) to induce epigenetic alteration and block hematopoietic differentiation. | r-2-hydroxyglutarate | isocitrate dehydrogenase (NADP(+)) 1 | Homo sapiens |
2 | Mutations of isocitrate dehydrogenase 1 (IDH1) and IDH2 in acute myeloid leukemia (AML) cells produce the oncometabolite R-2-hydroxyglutarate (R-2HG) to induce epigenetic alteration and block hematopoietic differentiation. | r-2-hydroxyglutarate | isocitrate dehydrogenase (NADP(+)) 1 | Homo sapiens |