Title : Doxorubicin Conjugated to Immunomodulatory Anticancer Lactoferrin Displays Improved Cytotoxicity Overcoming Prostate Cancer Chemo resistance and Inhibits Tumour Development in TRAMP Mice.

Pub. Date : 2016 Aug 31

PMID : 27576789






1 Functional Relationships(s)
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1 Orally fed iron saturated bLf-Dox inhibited tumour development, prolonged survival, reduced Dox induced general toxicity, cardiotoxicity, neurotoxicity in TRAMP mice and upregulated serum levels of anti-cancer molecules TNF-alpha, IFN-gamma, CCL4 and CCL17. Doxorubicin interferon gamma Mus musculus