Title : Cyclic Purine and Pyrimidine Nucleotides Bind to the HCN2 Ion Channel and Variably Promote C-Terminal Domain Interactions and Opening.

Pub. Date : 2016 Oct 4

PMID : 27568927






1 Functional Relationships(s)
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1 Here, we correlated the ability of cyclic nucleotides to promote interactions of isolated HCN2 C-terminal domains in solution with their ability to facilitate channel opening. Nucleotides, Cyclic hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 Homo sapiens