Title : Imeglimin prevents human endothelial cell death by inhibiting mitochondrial permeability transition without inhibiting mitochondrial respiration.

Pub. Date : 2016

PMID : 27551496






1 Functional Relationships(s)
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1 These cells were incubated in several oxidative stress environments (exposure to high glucose and oxidizing agent tert-butylhydroperoxide) which led to mitochondrial permeability transition pore (PTP) opening, cytochrome c release and cell death. tert-Butylhydroperoxide cytochrome c, somatic Homo sapiens