Pub. Date : 2017 Feb 15
PMID : 27550999
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | In contrast, 62.5% of mice that received vehicle control presented with palpable tumor recurrences within this time period (P = 0.0097).Conclusions: Collectively, these data demonstrate that therapeutic inhibition of MDM2-p53 interaction by MI-773 decreased the CSC fraction, sensitized ACC xenograft tumors to cisplatin, and eliminated tumor recurrence. | Cisplatin | transformed mouse 3T3 cell double minute 2 | Mus musculus |