Title : Validation of the high-performance of pyrosequencing for clinical MGMT testing on a cohort of glioblastoma patients from a prospective dedicated multicentric trial.

Pub. Date : 2016 Sep 20

PMID : 27542245






1 Functional Relationships(s)
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1 METHODS: The MGMT status of 139 glioblastoma patients, whom had received standard first line treatment, was determined using pyrosequencing (PSQ) and a semi-quantitative Methylation-specific PCR (sqMS-PCR) method, using both frozen and formalin-fixed paraffin-embedded FFPE samples. Formaldehyde O-6-methylguanine-DNA methyltransferase Homo sapiens