Pub. Date : 2016 Aug 17
PMID : 27535620
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | To test the hypothesis that corticosterone effectively suppresses adrenocorticotropic hormone (ACTH) without the metabolic adverse effects of cortisol, we infused cortisol or corticosterone in patients with Addison"s disease. | Corticosterone | proopiomelanocortin | Homo sapiens |
| 2 | To test the hypothesis that corticosterone effectively suppresses adrenocorticotropic hormone (ACTH) without the metabolic adverse effects of cortisol, we infused cortisol or corticosterone in patients with Addison"s disease. | Corticosterone | proopiomelanocortin | Homo sapiens |
| 3 | These data indicate that corticosterone may be a metabolically favorable alternative to cortisol for glucocorticoid replacement therapy when ACTH suppression is desirable, as in congenital adrenal hyperplasia, and justify development of a pharmaceutical preparation. | Corticosterone | proopiomelanocortin | Homo sapiens |