Pub. Date : 2016 Nov
PMID : 27528706
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | We demonstrate, using direct pharmacologic and genetic inhibition of RSK1/2, that these kinases contribute to the TNBC metastatic process in vivo Kinase profiling showed that RSK1 and RSK2 are the predominant kinases targeted by the new inhibitor, which is based on the natural product SL0101. | SL0101 | ribosomal protein S6 kinase A1 | Homo sapiens |
2 | We demonstrate, using direct pharmacologic and genetic inhibition of RSK1/2, that these kinases contribute to the TNBC metastatic process in vivo Kinase profiling showed that RSK1 and RSK2 are the predominant kinases targeted by the new inhibitor, which is based on the natural product SL0101. | SL0101 | ribosomal protein S6 kinase A1 | Homo sapiens |