Pub. Date : 2016 Aug 11
PMID : 27510168
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The caffeine-binding adenosine A2A receptor induces age-like HPA-axis dysfunction by targeting glucocorticoid receptor function. | Caffeine | adenosine A2a receptor | Homo sapiens |
| 2 | Caffeine is associated with procognitive effects in humans by counteracting overactivation of the adenosine A2A receptor (A2AR), which is upregulated in the human forebrain of aged and Alzheimer"s disease (AD) patients. | Caffeine | adenosine A2a receptor | Homo sapiens |
| 3 | Caffeine is associated with procognitive effects in humans by counteracting overactivation of the adenosine A2A receptor (A2AR), which is upregulated in the human forebrain of aged and Alzheimer"s disease (AD) patients. | Caffeine | adenosine A2a receptor | Homo sapiens |
| 4 | This supports the idea that the procognitive effects of A2AR antagonists, namely caffeine, on Alzheimer"s and age-related cognitive impairments may rely on its ability to modulate GR actions. | Caffeine | adenosine A2a receptor | Homo sapiens |