Title : Bendamustine increases interleukin-10 secretion from B cells via p38 MAP kinase activation.

Pub. Date : 2016 Oct

PMID : 27500457






1 Functional Relationships(s)
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1 Importantly, when PBMC from healthy donors were cultured with bendamustine at the concentration of 30muM, under the stimulation with an anti-IgM antibody, an anti-CD40 antibody, recombinant human IL-21 (rhIL-21) and recombinant human soluble BAFF (rhsBAFF), IL-10 production by B cells (CD20+CD4-CD8-CD14-) among peripheral blood mononuclear cell (PBMC) was significantly enhanced by adding bendamustine. Bendamustine Hydrochloride keratin 20 Homo sapiens