Pub. Date : 2016 Nov
PMID : 27485471
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In the present study, we evaluated histone H3 acetylation levels of bone marrow CD8+ T cells in SAA patients, and analyzed its correlation with clinical condition parameters. | saa | CD8a molecule | Homo sapiens |
| 2 | We found that the percentages of CD8+ T cell histone H3 acetylation in patients with untreated SAA, recovering SAA (R-SAA) and normal control, were 1.21 +- 0.08, 1.05 +- 0.36, and 1.00 +- 0.41, respectively, with no significant statistical differences. | saa | CD8a molecule | Homo sapiens |
| 3 | We found that the percentages of CD8+ T cell histone H3 acetylation in patients with untreated SAA, recovering SAA (R-SAA) and normal control, were 1.21 +- 0.08, 1.05 +- 0.36, and 1.00 +- 0.41, respectively, with no significant statistical differences. | saa | CD8a molecule | Homo sapiens |
| 4 | However, the amount of CD8+ T cell histone H3 acetylation from untreated SAA was 176.21 +- 32.22 mug/mg protein, which was significantly higher than that of complete response (CR)-SAA (104.29 +- 62.06 mug/mg protein) and normal control (133.94 +- 56.27 mug/mg protein) (P < 0.05) groups. | saa | CD8a molecule | Homo sapiens |
| 5 | Abnormal histone H3 acetylation of CD8+ T cells may thus play a role in the immune pathogenesis of SAA. | saa | CD8a molecule | Homo sapiens |