Pub. Date : 2016 Apr
PMID : 27482548
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Microtubule-Mediated Misregulation of Junctophilin-2 Underlies T-Tubule Disruptions and Calcium Mishandling in mdx Mice. | Calcium | junctophilin 2 | Mus musculus |
| 2 | Recently, improper trafficking of junctophilin-2 on an altered microtubule network caused t-tubule derangements and calcium mishandling in a pressure-overload heart failure model. | Calcium | junctophilin 2 | Mus musculus |
| 3 | Here, we investigated the hypothesis that an inverse relationship between microtubules and junctophilin-2 underlies t-tubule disruptions and calcium mishandling in mdx cardiac myocytes. | Calcium | junctophilin 2 | Mus musculus |
| 4 | In summary, these results suggest microtubule-mediated misregulation of junctophilin-2 causes t-tubule derangements and altered calcium handling in mdx cardiac myocytes. | Calcium | junctophilin 2 | Mus musculus |