Title : Apigenin Reduces Proteasome Inhibition-Induced Neuronal Apoptosis by Suppressing the Cell Death Process.

Pub. Date : 2016 Nov

PMID : 27473386






1 Functional Relationships(s)
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1 Apigenin attenuated the proteasome inhibitors (MG132 and MG115)-induced decrease in the levels of Bid and Bcl-2, increase in the levels of Bax and p53, loss of the mitochondrial transmembrane potential, release of cytochrome c, activation of caspases (-8, -9 and -3), cleavage of PARP-1 and cell death in both cell lines. benzyloxycarbonylleucyl-leucyl-leucine aldehyde tumor protein p53 Homo sapiens