Title : Interferon β improves the efficacy of low dose cisplatin by inhibiting NF-κB/p-Akt signaling on HeLa cells.

Pub. Date : 2016 Aug

PMID : 27470347






2 Functional Relationships(s)
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1 Additionally, the expression of active PARP was significantly increased and MMP-9 level was decreased in combination group as compared to the expression seen for the treatment with interferon beta or cisplatin alone. Cisplatin collagen type XI alpha 2 chain Homo sapiens
2 Results demonstrate that the synergistic inhibitory effects of interferon beta and low dose of cisplatin on human cervical cancer cells and also suggest that the inhibition of NF-kappaB/p-Akt signaling pathway plays a critical role in the anticancer effects of combination treatment along with the induction of PARP. Cisplatin collagen type XI alpha 2 chain Homo sapiens