Title : Synergistic inhibition of characteristics of liver cancer stem-like cells with a combination of sorafenib and 8-bromo-7-methoxychrysin in SMMC-7721 cell line.

Pub. Date : 2016 Sep

PMID : 27461522






1 Functional Relationships(s)
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1 Sorafenib diminished the self-renewal capacity and downregulated the expression of stem cell biomarkers (CD133, CD44 and ALDH1) in a dose-dependent manner, while BrMC cooperated with sorafenib to strengthen this inhibition. Sorafenib aldehyde dehydrogenase 1 family member A1 Homo sapiens