Title : Ezetimibe increases intestinal expression of the LDL receptor gene in dyslipidaemic men with insulin resistance.

Pub. Date : 2016 Dec

PMID : 27460541






2 Functional Relationships(s)
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1 Treatment with ezetimibe significantly increased intestinal LDLR (+16.2%; P = .01), 3-hydroxy-3-methyl-glutaryl-CoA reductase (HMG-CoAR; +14.0%; P = .04) and acetyl-Coenzyme A acetyltransferase 2 (ACAT-2) mRNA expression (+12.5%; P = .03). Ezetimibe acetyl-CoA acetyltransferase 2 Homo sapiens
2 Treatment with ezetimibe significantly increased intestinal LDLR (+16.2%; P = .01), 3-hydroxy-3-methyl-glutaryl-CoA reductase (HMG-CoAR; +14.0%; P = .04) and acetyl-Coenzyme A acetyltransferase 2 (ACAT-2) mRNA expression (+12.5%; P = .03). Ezetimibe acetyl-CoA acetyltransferase 2 Homo sapiens