Title : Structural insights into HDAC6 tubulin deacetylation and its selective inhibition.

Pub. Date : 2016 Sep

PMID : 27454931






2 Functional Relationships(s)
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1 We report crystal structures of zebrafish histone deacetylase 6 (HDAC6) catalytic domains in tandem or as single domains in complex with the (R) and (S) enantiomers of trichostatin A (TSA) or with the HDAC6-specific inhibitor nexturastat A. 4-((1-butyl-3-phenylureido)methyl)-N-hydroxybenzamide histone deacetylase 6 Danio rerio
2 We report crystal structures of zebrafish histone deacetylase 6 (HDAC6) catalytic domains in tandem or as single domains in complex with the (R) and (S) enantiomers of trichostatin A (TSA) or with the HDAC6-specific inhibitor nexturastat A. 4-((1-butyl-3-phenylureido)methyl)-N-hydroxybenzamide histone deacetylase 6 Danio rerio