Title : Steric structure-activity relationship of cyproheptadine derivatives as inhibitors of histone methyltransferase Set7/9.

Pub. Date : 2016 Sep 15

PMID : 27448773






2 Functional Relationships(s)
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1 Steric structure-activity relationship of cyproheptadine derivatives as inhibitors of histone methyltransferase Set7/9. Cyproheptadine SET domain containing 7, histone lysine methyltransferase Homo sapiens
2 We previously identified cyproheptadine, which has a characteristic butterfly-like molecular conformation with bent tricyclic dibenzosuberene and chair-form N-methylpiperidine moieties, as a Set7/9 inhibitor. Cyproheptadine SET domain containing 7, histone lysine methyltransferase Homo sapiens