Title : Ameliorative effect of dietary genistein on diabetes induced hyper-inflammation and oxidative stress during early stage of wound healing in alloxan induced diabetic mice.

Pub. Date : 2016 Sep 23

PMID : 27431618






1 Functional Relationships(s)
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1 Moreover, genistein supplementation restored NLRP3 inflammasome (NLRP3, ASC and caspase-1) at the basal level and ameliorated both inflammation (TNFalpha, iNOS, COX2 and NFkappaB) and antioxidant defense system (Nrf2, HO-1, GPx, and catalase) during early stage of wound healing in diabetic mice. Genistein nitric oxide synthase 2, inducible Mus musculus