Pub. Date : 2016 Oct
PMID : 27427966
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Here I review our studies on the final stages of the yeast secretory pathway that have led us to propose that adjacent Rabs on a pathway are networked to one another through their regulators; specifically we have shown that the Rab, Ypt32, in its GTP-bound form recruits both Sec2, the GEF that activates the downstream Rab, Sec4, as well as Gyp1, the GAP that inactivates the upstream Rab, Ypt1. | rabs | guanine nucleotide exchange factor SEC2 | Saccharomyces cerevisiae S288C |