Title : Nanoparticle-Mediated Delivery of Irbesartan Induces Cardioprotection from Myocardial Ischemia-Reperfusion Injury by Antagonizing Monocyte-Mediated Inflammation.

Pub. Date : 2016 Jul 11

PMID : 27403534






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1 Here we develop bioabsorbable poly-lactic/glycolic acid (PLGA) nanoparticles incorporating irbesartan, an angiotensin II type 1 receptor blocker with a peroxisome proliferator-activated receptor (PPAR)gamma agonistic effect (irbesartan-NP). Irbesartan angiotensin II receptor type 1 Homo sapiens