Pub. Date : 2016 Nov
PMID : 27396856
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Hypoxanthine markedly increased serum cholesterol levels and the atherosclerotic plaque area in Apoe KO mice. | Hypoxanthine | apolipoprotein E | Mus musculus |
| 2 | Hypoxanthine and APOE knockdown using APOE-siRNA synergistically induced cholesterol accumulation and reduced APOE and ABCA1 expression. | Hypoxanthine | apolipoprotein E | Mus musculus |
| 3 | Hypoxanthine and APOE knockdown using APOE-siRNA synergistically induced cholesterol accumulation and reduced APOE and ABCA1 expression. | Hypoxanthine | apolipoprotein E | Mus musculus |
| 4 | Hypoxanthine induces cholesterol accumulation in hepatic cells through alterations in enzymes that control lipid transport and induces atherosclerosis in APOE-deficient cells and mice. | Hypoxanthine | apolipoprotein E | Mus musculus |