Title : Nicotinamide N-methyltransferase catalyses the N-methylation of the endogenous β-carboline norharman: evidence for a novel detoxification pathway.

Pub. Date : 2016 Oct 1

PMID : 27389312






1 Functional Relationships(s)
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1 It has been proposed that NNMT may possess beta-carboline (BC) N-methyltransferase activity, endogenously and exogenously produced pyridine-containing compounds which, when N-methylated, are potent inhibitors of Complex I and have been proposed to have a role in the pathogenesis of Parkinson"s disease. pyridine nicotinamide N-methyltransferase Homo sapiens