Title : [Interferon-β combined with all-trans retinoic acid supresses proliferation and promote apoptosis by inhibiting JAK2/STAT3 pathway in HepG2 human hepatocellular carcinoma cells].

Pub. Date : 2016 Jul

PMID : 27363269






1 Functional Relationships(s)
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1 The expressions of p-JAK2 and p-STAT3 were down-regulated while the expressions of GRIM-19 and Bax were up-regulated after treated with IFN-beta or ATRA on HepG2 cells, especially the combination of IFN-beta and ATRA. Tretinoin BCL2 associated X, apoptosis regulator Homo sapiens