Title : The epoxyeicosatrienoic acid analog PVPA ameliorates cyclosporine-induced hypertension and renal injury in rats.

Pub. Date : 2016 Sep 1

PMID : 27358055






1 Functional Relationships(s)
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1 Cytochrome P-450 epoxygenase metabolites of arachidonic acid, epoxyeicosatrienoic acids (EETs), have potent vasodilator and antihypertensive properties in addition to many cytoprotective effects, but their effects on CNI-induced nephrotoxicity have not been explored. epoxyeicosatrienoic acids cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus