Title : In vivo genome-wide profiling reveals a tissue-specific role for 5-formylcytosine.

Pub. Date : 2016 Jun 29

PMID : 27356509






5 Functional Relationships(s)
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1 BACKGROUND: Genome-wide methylation of cytosine can be modulated in the presence of TET and thymine DNA glycosylase (TDG) enzymes. Cytosine thymine DNA glycosylase Mus musculus
2 BACKGROUND: Genome-wide methylation of cytosine can be modulated in the presence of TET and thymine DNA glycosylase (TDG) enzymes. Cytosine thymine DNA glycosylase Mus musculus
3 Changes in the formylation profile of cytosine upon depletion of TDG suggest TET/TDG-mediated active demethylation occurs preferentially at intron-exon boundaries and reveals a major role for TDG in shaping 5fC distribution at CpG islands. Cytosine thymine DNA glycosylase Mus musculus
4 Changes in the formylation profile of cytosine upon depletion of TDG suggest TET/TDG-mediated active demethylation occurs preferentially at intron-exon boundaries and reveals a major role for TDG in shaping 5fC distribution at CpG islands. Cytosine thymine DNA glycosylase Mus musculus
5 Changes in the formylation profile of cytosine upon depletion of TDG suggest TET/TDG-mediated active demethylation occurs preferentially at intron-exon boundaries and reveals a major role for TDG in shaping 5fC distribution at CpG islands. Cytosine thymine DNA glycosylase Mus musculus