Title : Differential effects of phorbol esters on PGE2 and bradykinin-induced elevation of [Cai2+] in MDCK cells.

Pub. Date : 1989 Jun

PMID : 2735424






3 Functional Relationships(s)
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1 In contrast to complete blockade by 10(-8) PMA of the PGE2 (10(-5) M)-elicited Ca2+ transient, this concentration of PMA inhibited the Ca2+ transient evoked by 10(-9) M bradykinin (BK) by 50%. Tetradecanoylphorbol Acetate kininogen 1 Canis lupus familiaris
2 In contrast to complete blockade by 10(-8) PMA of the PGE2 (10(-5) M)-elicited Ca2+ transient, this concentration of PMA inhibited the Ca2+ transient evoked by 10(-9) M bradykinin (BK) by 50%. Tetradecanoylphorbol Acetate kininogen 1 Canis lupus familiaris
3 In fact 10(-4) M PMA only partially blocked the BK-elicited Ca2+ transient. Tetradecanoylphorbol Acetate kininogen 1 Canis lupus familiaris