Pub. Date : 2016 Jun 23
PMID : 27346397
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | [Mifepristone inhibites the migration of endometrial cancer cells through regulating H19 methylation]. | Mifepristone | H19 imprinted maternally expressed transcript | Homo sapiens |
| 2 | In the Ishikawa cells, mifepristone suppressed the transcriptional level of H19 through enhancing its promoter methylation, which resulted in inhibited expressions of HMGA2 and vimentin and increased expression of E-cadherin in a time- and concentration-dependent manner. | Mifepristone | H19 imprinted maternally expressed transcript | Homo sapiens |
| 3 | CONCLUSION: Mifepristone inhibits the migration of endometrial carcinoma cells partially through methylation-induced of transcriptional inhibition of H19, which results in the down-regulation of HMGA2 and vimentin and upregulation of E-cadherin. | Mifepristone | H19 imprinted maternally expressed transcript | Homo sapiens |