Title : Attenuation of Ischemia-Reperfusion Injury and Improvement of Survival in Recipients of Steatotic Rat Livers Using CD47 Monoclonal Antibody.

Pub. Date : 2016 Jul

PMID : 27331362






1 Functional Relationships(s)
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1 RESULTS: Administration of CD47mAb400 to donor livers increased recipient survival and resulted in significant reduction of serum transaminases, bilirubin, triphosphate nick-end labeling staining, caspase-3 activity, oxidative and nitrosative stresses, and proinflammatory cytokine expression of TNF-alpha, IL-6 and IL-1beta. Bilirubin CD47 molecule Homo sapiens