Title : Downregulation of vimentin expression increased drug resistance in ovarian cancer cells.

Pub. Date : 2016 Jul 19

PMID : 27322682






1 Functional Relationships(s)
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1 Our results also revealed that vimentin knockdown increased the 14-3-3 mediated retention of Cdc25C in the cytoplasm, leading to inactivation of Cdk1 and the prolonged G2 phase arrest that allowed the longer period of time for cells to repair cisplatin-damaged DNA. Cisplatin cell division cycle 25C Homo sapiens