Pub. Date : 2016 Oct 4
PMID : 27318982
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Synthesis and biological evaluation of novel FK228 analogues as potential isoform selective HDAC inhibitors. | romidepsin | histone deacetylase 9 | Homo sapiens |
| 2 | This study demonstrated that simple modification at the C4 and C7 side chains in FK228 is effective for improving both HDAC inhibitory activity and isoform selectivity; moreover, potent and highly isoform-selective class I HDAC1 inhibitors were identified. | romidepsin | histone deacetylase 9 | Homo sapiens |