Title : Urinary excretion of metallothionein-I and its degradation product in rats treated with cadmium, copper, zinc or mercury.

Pub. Date : 1989 May 31

PMID : 2728004






4 Functional Relationships(s)
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1 Urinary excretion of metallothionein-I and its degradation product in rats treated with cadmium, copper, zinc or mercury. Cadmium metallothionein 1 Rattus norvegicus
2 The metallothionein-I (MT-I) content of urine following administration of cadmium (Cd), copper (Cu), mercury (Hg) or zinc (Zn) to rats was determined by radioimmunoassay. Cadmium metallothionein 1 Rattus norvegicus
3 The metallothionein-I (MT-I) content of urine following administration of cadmium (Cd), copper (Cu), mercury (Hg) or zinc (Zn) to rats was determined by radioimmunoassay. Cadmium metallothionein 1 Rattus norvegicus
4 Fractionation of urine from Cd-treated rats on Sephadex G-50 showed a single immunoreactive component corresponding to native MT-I, whereas in urine from Cu, Zn or Hg-treated rats 2 immunoreactive components corresponding to MT-I and a possible degradation production were observed. Cadmium metallothionein 1 Rattus norvegicus