Pub. Date : 2016 Aug
PMID : 27267892
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We therefore investigated the hypothesis that Ptprt-knockout (KO) mice would be more susceptible to 4-NQO-induced oral carcinogenesis and more sensitive to Stattic-mediated chemoprevention compared with wild-type (WT) mice. | 4-Nitroquinoline-1-oxide | protein tyrosine phosphatase, receptor type, T | Mus musculus |
| 2 | Herein, we demonstrate that Ptprt WT and KO mice develop similar spectra of HNSCC disease severity upon 12 weeks of 4-NQO administration, with no apparent effect of Ptprt genotype on carcinogenesis or treatment outcome. | 4-Nitroquinoline-1-oxide | protein tyrosine phosphatase, receptor type, T | Mus musculus |