Pub. Date : 2016 Jun 28
PMID : 27259258
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Sorafenib/pazopanib combined with sildenafil in a [GRP78+HSP27] -dependent fashion to: (i) profoundly activate an eIF2alpha/Beclin1 pathway; (ii) profoundly inactivate mTOR and increase ATG13 phosphorylation, collectively resulting in the formation of toxic autophagosomes. | Sorafenib | heat shock protein family B (small) member 1 | Homo sapiens |