Title : Protein kinase A-dependent phosphorylation stimulates the transcriptional activity of hypoxia-inducible factor 1.

Pub. Date : 2016 May 31

PMID : 27245613






1 Functional Relationships(s)
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1 Furthermore, increased cAMP concentrations enhanced the expression of HIF target genes encoding CD39 and CD73, which are enzymes that convert extracellular adenosine 5"-triphosphate to adenosine, a molecule that enhances tumor immunosuppression and reduces heart rate and contractility. Cyclic AMP 5'-nucleotidase ecto Homo sapiens