Title : Interferon β (IFN-β) Production during the Double-stranded RNA (dsRNA) Response in Hepatocytes Involves Coordinated and Feedforward Signaling through Toll-like Receptor 3 (TLR3), RNA-dependent Protein Kinase (PKR), Inducible Nitric Oxide Synthase (iNOS), and Src Protein.

Pub. Date : 2016 Jul 15

PMID : 27226571






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The phosphorylation of TLR3 on tyrosine 759 was shown to increase in parallel to IFN-beta production in an iNOS- and Src-dependent manner, and Src was found to directly interact with TLR3 in the endosomal compartment of poly(I:C)-treated cells. Tyrosine toll like receptor 3 Homo sapiens