Title : Structural Basis for Bulky-Adduct DNA-Lesion Recognition by the Nucleotide Excision Repair Protein Rad14.

Pub. Date : 2016 Jul 25

PMID : 27223336






1 Functional Relationships(s)
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1 Here we present the synthesis of DNA molecules containing the polycyclic, aromatic amine C8-guanine lesions acetylaminophenyl, acetylaminonaphthyl, acetylaminoanthryl, and acetylaminopyrenyl, as well as their crystal structures in complex with the yeast XPA homologue Rad14. aromatic amine DNA repair protein RAD14 Saccharomyces cerevisiae S288C