Title : Inhibition of mTOR suppresses human gallbladder carcinoma cell proliferation and enhances the cytotoxicity of 5-fluorouracil by downregulating MDR1 expression.

Pub. Date : 2016 May

PMID : 27212159






1 Functional Relationships(s)
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1 CONCLUSIONS: Dual mTORC1/mTORC2 inhibitors such as OSI-027 are promising therapeutic agents in combination with 5-FU for the treatment of human gallbladder cancer. OSI 027 CREB regulated transcription coactivator 1 Mus musculus