Title : Disruption of the HPA-axis through corticosterone-release pellets induces robust depressive-like behavior and reduced BDNF levels in mice.

Pub. Date : 2016 Jul 28

PMID : 27208833






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1 Disruption of the HPA-axis through corticosterone-release pellets induces robust depressive-like behavior and reduced BDNF levels in mice. Corticosterone brain derived neurotrophic factor Mus musculus
2 We show that three weeks of corticosterone pellet exposure robustly induces depressive-like but not anxiety-like behavior in mice, accompanied by a significant decrease in hippocampal brain-derived neurotrophic factor levels, at five weeks after the start of treatment. Corticosterone brain derived neurotrophic factor Mus musculus