Title : Stilbenoids remodel the DNA methylation patterns in breast cancer cells and inhibit oncogenic NOTCH signaling through epigenetic regulation of MAML2 transcriptional activity.

Pub. Date : 2016 Jul

PMID : 27207652






1 Functional Relationships(s)
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1 This condensed chromatin structure is associated with binding of DNMT3B and decreased occupancy of OCT1 transcription factor at MAML2 enhancer, suggesting a role of DNMT3B in increasing methylation of MAML2 after stilbenoid treatment. stilbenoid DNA methyltransferase 3 beta Homo sapiens