Title : Effect of H-7 on the modulation of glucagon actions by activators of protein kinase-C.

Pub. Date : 1989 Jan

PMID : 2719714






2 Functional Relationships(s)
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1 The stimulations of ureagenesis and cyclic AMP accumulation induced by glucagon were inhibited by 10 nM vasopressin or 100 nM phorbol 12-myristate 13-acetate (PMA). Glucagon arginine vasopressin Rattus norvegicus
2 H-7 blocked the inhibition of glucagon-stimulated ureagenesis induced by PMA and vasopressin and diminished their effect on the accumulation of cyclic AMP induced by glucagon. Glucagon arginine vasopressin Rattus norvegicus