Title : Oxidative stress and dysfunctional NRF2 underlie pachyonychia congenita phenotypes.

Pub. Date : 2016 Jun 1

PMID : 27183391






1 Functional Relationships(s)
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1 Topical application of the NRF2 activator sulforaphane to the footpad of Krt16-/- mice prevented the development of PPK and normalized redox balance via regeneration of GSH from existing cellular pools. sulforaphane keratin 16 Mus musculus