Title : Synthesis and characterization of a pH responsive folic acid functionalized polymeric drug delivery system.

Pub. Date : 2016 Jul-Aug

PMID : 27183249






2 Functional Relationships(s)
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1 We report the computational analysis, synthesis and characterization of folate functionalized poly(styrene-alt-maleic anhydride), PSMA for drug delivery purpose. Folic Acid folate hydrolase 1 Homo sapiens
2 The computational results showed the bio-degradable linker 2, 4-diaminobutyric acid, DABA as a good candidate allowing flexibility of the folic acid group while maintaining the pH sensitivity of PSMA, used as a trigger for drug release. Folic Acid folate hydrolase 1 Homo sapiens