Pub. Date : 2016 Nov
PMID : 27178737
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Exenatide treatment decreases fasting fibroblast growth factor 21 levels in patients with newly diagnosed type 2 diabetes mellitus. | Exenatide | fibroblast growth factor 21 | Homo sapiens |
| 2 | The aim of this study was to investigate the effects of the glucagon-like peptide (GLP)-1 receptor agonist exenatide on FGF21 levels and other metabolic parameters in patients with newly diagnosed T2DM. | Exenatide | fibroblast growth factor 21 | Homo sapiens |
| 3 | In T2DM patients, exenatide treatment resulted in decreases in BMI, HbA1c, total cholesterol and triglycerides, and also in FGF21 (149.17+-81.36 vs 102.17+-64.12ng/mL; P<0.01). | Exenatide | fibroblast growth factor 21 | Homo sapiens |
| 4 | CONCLUSION: Besides the improvement in insulin resistance and recovery of beta-cell function, 12 weeks of exenatide treatment may also play a role in lowering FGF21 levels in T2DM patients. | Exenatide | fibroblast growth factor 21 | Homo sapiens |