Title : The ceramide-activated protein phosphatase Sit4p controls lifespan, mitochondrial function and cell cycle progression by regulating hexokinase 2 phosphorylation.

Pub. Date : 2016 Jun 17

PMID : 27163342






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Sit4p is the catalytic subunit of a ceramide-activated PP2A-like phosphatase that regulates cell cycle, mitochondrial function, oxidative stress resistance and chronological lifespan in yeast. Ceramides type 2A-related serine/threonine-protein phosphatase SIT4 Saccharomyces cerevisiae S288C