Title : Deferoxamine-induced increase in the intracellular iron levels in highly aggressive breast cancer cells leads to increased cell migration by enhancing TNF-α-dependent NF-κB signaling and TGF-β signaling.

Pub. Date : 2016 Jul

PMID : 27138103






2 Functional Relationships(s)
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1 Deferoxamine-induced increase in the intracellular iron levels in highly aggressive breast cancer cells leads to increased cell migration by enhancing TNF-alpha-dependent NF-kappaB signaling and TGF-beta signaling. Iron tumor necrosis factor Homo sapiens
2 Collectively, our study has provided the first evidence suggesting that increased intracellular iron levels could lead to enhanced migration of aggressive breast cancer cells by increasing TNF-alpha-dependent NF-kappaB signaling and TGF-beta signaling. Iron tumor necrosis factor Homo sapiens