Pub. Date : 2016 May
PMID : 27133418
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The observation that the levels of FPP and GGPP, but not that of cholesterol, are elevated in AD patients is consistent with the finding that statins, competitive inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, reduce FPP and GGPP levels and amyloid beta protein production in preclinical studies. | farnesyl pyrophosphate | 3-hydroxy-3-methylglutaryl-CoA reductase | Homo sapiens |
| 2 | The observation that the levels of FPP and GGPP, but not that of cholesterol, are elevated in AD patients is consistent with the finding that statins, competitive inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, reduce FPP and GGPP levels and amyloid beta protein production in preclinical studies. | farnesyl pyrophosphate | 3-hydroxy-3-methylglutaryl-CoA reductase | Homo sapiens |