Title : Cannabidiol attenuates haloperidol-induced catalepsy and c-Fos protein expression in the dorsolateral striatum via 5-HT1A receptors in mice.

Pub. Date : 2016 Aug 1

PMID : 27131780






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1 To further investigate this latter effect, we tested whether CBD (15-60mg/kg) would attenuate the catalepsy and c-Fos protein expression in the dorsal striatum induced by haloperidol (0.6mg/kg). Haloperidol FBJ osteosarcoma oncogene Mus musculus
2 Haloperidol also increased c-Fos protein expression in the dorsolateral striatum, an effect attenuated by previous CBD administration. Haloperidol FBJ osteosarcoma oncogene Mus musculus
3 CBD effects on catalepsy and c-Fos protein expression induced by haloperidol were blocked by the 5-HT1A receptor antagonist. Haloperidol FBJ osteosarcoma oncogene Mus musculus